Therapy and Management | Management | Prevention

Approaching asthma prevention on different levels

Although asthma symptoms can be well controlled with appropriate pharmacological therapy every effort must be undertaken to prevent development and worsening of this chronic incurable disease.

Primary prevention is introduced to prevent the onset of disease in individuals at risk. Allergic sensitisation, which can occur pre- or postnatally, seems to be the most common precursor in the development of asthma. Yet little evidence has been established concerning particular interventions. However it is generally accepted, that prenatal maternal smoking increases the risk of respiratory diseases during infancy and childhood.

After sensitisation has developed secondary preventive measures aim at preventing the establishment of chronic persistent disease. Recent focus lies on interventions during the first two years of life. Like in primary prevention studies on particular measures have to be confirmed before recommended.

Tertiary prevention aims at avoiding the exposure of susceptible individuals to particular allergens after asthma is established. Although histopathological evidence suggests that disease is fully established by the time asthma symptoms occur avoidance of identified allergens is essential for the prevention of acute exacerbations and emergency situations. Additionally patients with moderate to severe asthma should be advised to have an influenza vaccination every year.

Literature:

Jones CA, Holloway JA, Warner JO. Does atopic disease start in foetal life? 2000. Allergy ; 55: 2-10

Moller C, Dreborg S, Ferdousi HA, Halken S, Host A, Jacobsen L, Koivikko A, Koller DY, Niggemann B, Norberg LA, Urbanek R, Valovirta E, Wahn U. Pollen immunotherapy reduces the development of asthma in children with seasonal rhiniconjunctivitis (the PAT study). 2002. J Allergy Clin Immunol ; 109 (2): 251-256

O'Byrne P. GINA Executive Commitee. Global strategy for asthma management and prevention. 2004. National Institutes of Health. Publication No 02-3659

DiFranza JR, Aligne CA, Weitzman M. Prenatal and postnatal environmental tobacco exposure and children's health. 2004. Pediatrics; 113 (Suppl. 4): 1007-1015

Warner IO, Warner JA, Pohunek P, Rao R, Marguet C, Clough B et al. Markers of allergy and inflammation. 1998. Pediatr Allergy Immunol ; 9: 53-57

Primary, secondary, and tertiary measures of prevention

Select language

Search

Contact

Do you have questions?
Contact our experts...


Contact