Characteristics of the Twisthaler® dry powder inhaler
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The Twisthaler® is an inhalation device relatively independent of flow rates. It has been demonstrated that with inspiratory flows between 28 l/min and 60 l/min 91% to 112% of the metered dose is delivered at the mouthpiece. The fraction of particles smaller than 6.5 µm amounts up to 40% at an inspiratory flow of 60 l/min. Additionally drug doses released from the Twisthaler® only vary slightly between each dose. The Twisthaler® is approved for mometasone furoate (Asmanex®). Literature: Voshaar T. Therapie mit Aerosolen. 2005. Uni-Med: Bremen Yang TT, Li S, Wyka B, Kenyon D. Drug delivery performance of the mometasone furoate dry powder inhaler. 2001. Journal of Aerosol Medicine; 14 (4): 487-494 |
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Correct use of the Twisthaler®
Before removing the white cap ensure that the counter and the arrow on the base are in line with each other.
Hold the inhaler upright, grip the base and turn the cap anticlockwise.
Remove the cap from the mouthpiece. Removing the cap causes the dose counter to count down.
Insert the mouthpiece in your mouth and close your lips around it.
Breathe in rapidly and deeply.
Remove the inhaler and hold your breath for as long as is comfortable.
Breathe out through the nose.
Replace the cap immediately after each inhalation.
